منابع مشابه
TRIALS ON TRIAL Interpreting the results of a clinical trial
Elements of an interpretation Authors are generally encouraged to summarise which the results and findings are consistent with hypothesis, and to comment on the robustness of drawing conclusions and making recommendations n ex pla I preparing an article reporting a clinical trial, the authors are pected to provide a reasoned interpretation of the results and ce them into a broader clinical cont...
متن کاملInterpreting and reporting clinical trials with results of borderline significance.
The quality of randomised clinical trials and how they are reported have improved over time, with clearer guidelines on conduct and statistical analysis.Clinical trials often take several years, but interpreting the results at the end is arguably the most important activity because it influences whether a new intervention is recommended or not. Although researchers have becomemore familiar with...
متن کاملInterpreting results of clinical trials: a conceptual framework.
C linical trials are generally designed to test the superiority of an intervention (e.g., treatment, procedure, or device) as compared with a control. Trials that claim superiority of an intervention most often try to reject the null hypothesis, which generally states that the effect of an intervention of interest is no different from the control. In this editorial, we introduce a conceptual fr...
متن کاملEvaluation of Clinical Trials
In a number of important clinical issues such as evaluation of the efficacy or effectiveness of therapeutic or preventive interventions as well as for comparing the harms of interventions, randomized controlled trials (RCTs) provide the highest levels of evidence, either directly or indirectly. It is obvious that critical appraisal of these studies to assess their validity and precision is of p...
متن کاملEvidence Based Medicine: Clinical Trials
Evidence based medicine is very important for success of modern medicine. It is the ongoing process of using the most reliable evidence from clinical studies, scientific understanding and medical practice to make the best possible medical choice for patients. Evidence based medicine is how medicine advances and how we get improvements in life expectancy and quality of life. It not only identifi...
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ژورنال
عنوان ژورنال: BMJ
سال: 1978
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.6150.1497-b